MR Imaging of Pediatric Musculoskeletal Tumors:: Recent Advances and Clinical Applications

Mi-Jung Lee; Avneesh Chhabra; Joseph G Pressey; Charles L Dumoulin; Hee Kyung Kim

doi:10.1016/j.mric.2019.01.010

MR Imaging of Pediatric Musculoskeletal Tumors:: Recent Advances and Clinical Applications

Magn Reson Imaging Clin N Am. 2019 May;27(2):341-371. doi: 10.1016/j.mric.2019.01.010.

Authors

Mi-Jung Lee¹, Avneesh Chhabra², Joseph G Pressey³, Charles L Dumoulin⁴, Hee Kyung Kim⁵

Affiliations

¹ Department of Radiology, Severance Hospital, Research Institute of Radiological Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seoul 03722, South Korea.
² Radiology Department, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA; Orthopedics Department, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
³ Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 5031, Cincinnati, OH 45229, USA.
⁴ Department of Radiology, Imaging Research Center, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 5031, Cincinnati, OH 45229, USA.
⁵ Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 5031, Cincinnati, OH 45229, USA; Department of Radiology, University of Cincinnati College of Medicine, 234 Goodman street, Cincinnati, OH 45219, USA. Electronic address: hee.kim@cchmc.org.

PMID: 30910102
DOI: 10.1016/j.mric.2019.01.010

Abstract

Pediatric musculoskeletal tumors comprise approximately 10% of childhood neoplasms, and MR imaging has been used as the imaging evaluation standard for these tumors. The role of MR imaging in these cases includes identification of tumor origin, tissue characterization, and definition of tumor extent and relationship to adjacent structures as well as therapeutic response in posttreatment surveillance. Technical advances have enabled quantitative evaluation of biochemical changes in tumors. This article reviews recent updates to MR imaging of pediatric musculoskeletal tumors, focusing on advanced MR imaging techniques and providing information on the relevant physics of these techniques, clinical applications, and pitfalls.

Keywords: Diffusion MR imaging; High-intensity focused ultrasound ablation; Magnetic resonance spectroscopy; Musculoskeletal; Pediatrics; Perfusion MR imaging; Whole-body imaging.

Publication types

Review

MeSH terms

Adolescent
Child
Child, Preschool
Female
Humans
Magnetic Resonance Imaging / methods*
Male
Musculoskeletal Diseases / diagnostic imaging*
Musculoskeletal System / diagnostic imaging