Evaluation of pazopanib cytotoxicity to normal vascular endothelial cells in vitro: A comment on Goto et al

J Dermatol. 2019 Sep;46(9):e341-e342. doi: 10.1111/1346-8138.14860. Epub 2019 Mar 25.

Authors

Shinya Kitamura¹, Teruki Yanagi¹, Takuya Maeda¹, Keisuke Imafuku¹, Hiroo Hata¹, Mikio Masuzawa², Hiroshi Shimizu¹

Affiliations

¹ Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
² Department of Molecular Diagnostics, School of Allied Health Sciences, Kitasato University, Sagamihara, Japan.

PMID: 30908708
DOI: 10.1111/1346-8138.14860

No abstract available

Publication types

Letter

MeSH terms

Angiogenesis Inhibitors / toxicity*
Apoptosis / drug effects
Cell Line, Tumor
Cell Survival / drug effects
Dermis / cytology
Endothelium, Vascular / cytology
Fibroblasts / drug effects
Hemangiosarcoma / drug therapy
Human Umbilical Vein Endothelial Cells / drug effects*
Humans
Indazoles
Pyrimidines / toxicity*
Skin Neoplasms / drug therapy
Sulfonamides / toxicity*
Toxicity Tests

Substances

Angiogenesis Inhibitors
Indazoles
Pyrimidines
Sulfonamides
pazopanib