Short tau inversion recovery magnetic resonance imaging for staging and screening in myxoid liposarcoma

Alexander Chien; Craig W Zuppan; Li Lei; Nadine L Williams; Troy G Shields; Joseph G Elsissy; Peter Pham; Lee M Zuckerman

doi:10.1016/j.jor.2019.02.023

Short tau inversion recovery magnetic resonance imaging for staging and screening in myxoid liposarcoma

J Orthop. 2019 Feb 28;16(3):206-210. doi: 10.1016/j.jor.2019.02.023. eCollection 2019 May-Jun.

Authors

Alexander Chien¹, Craig W Zuppan², Li Lei³, Nadine L Williams⁴, Troy G Shields⁴, Joseph G Elsissy⁴, Peter Pham¹, Lee M Zuckerman⁴

Affiliations

¹ Department of Radiology, Loma Linda University Medical Center, 11234 Anderson Street, Loma Linda, CA, 92354, USA.
² Department of Pathology, Loma Linda University School of Medicine, 11234 Anderson Street, Loma Linda, CA, 92354, USA.
³ Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Lane 235, Stanford, CA 94305-5324, USA.
⁴ Department of Orthopaedic Surgery, Loma Linda University Medical Center, 11406 Loma Linda Drive, Suite 218, Loma Linda, CA, 92354, USA.

Abstract

Purpose: Myxoid liposarcoma has a propensity to metastasize to bone. MRI is the preferred modality for detecting bone disease. We evaluated multiple MRI sequences to determine an optimal screening method.

Methods: Whole body MRI was performed on all patients. The number and locations of metastases found by imaging and round cell component of the sites sampled were evaluated.

Results: We found a total of 68 osseous lesions. Whole body MRI utilizing STIR only sequences decreased imaging time by 83.6% and demonstrated the lesions the best.

Conclusions: STIR sequences can be exclusively used during staging and screening of myxoid liposarcoma.

Keywords: Magnetic resonance imaging (MRI); Myxoid liposarcoma; Screening; Skeletal metastases.