Nanostructured titanium oxide hybrids-based electrochemical biosensors for healthcare applications

Nagaraj P Shetti; Shikandar D Bukkitgar; Kakarla Raghava Reddy; Ch Venkata Reddy; Tejraj M Aminabhavi

doi:10.1016/j.colsurfb.2019.03.013

Nanostructured titanium oxide hybrids-based electrochemical biosensors for healthcare applications

Colloids Surf B Biointerfaces. 2019 Jun 1:178:385-394. doi: 10.1016/j.colsurfb.2019.03.013. Epub 2019 Mar 16.

Authors

Nagaraj P Shetti¹, Shikandar D Bukkitgar², Kakarla Raghava Reddy³, Ch Venkata Reddy⁴, Tejraj M Aminabhavi⁵

Affiliations

¹ Electrochemistry and Materials Group, Department of Chemistry, K. L. E. Institute of Technology, Gokul, Hubballi 580030, India(1). Electronic address: dr.npshetti@gmail.com.
² Electrochemistry and Materials Group, Department of Chemistry, K. L. E. Institute of Technology, Gokul, Hubballi 580030, India(1).
³ School of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, NSW 2006, Australia. Electronic address: reddy.chem@gmail.com.
⁴ School of Mechanical Engineering, Yeungnam University, Gyengsan 712-749, South Korea. Electronic address: cvrphy@gmail.com.
⁵ Sonia College of Pharmacy, Dharwad, 580 002, Karnataka, India.

PMID: 30903977
DOI: 10.1016/j.colsurfb.2019.03.013

Abstract

Biosensors are promising biotechnology products that can be widely used for environmental monitoring, food analysis, and healthcare diagnostics. To detect analytes of interest, the use of nanotechnology in bio-analytical devices is advantageous for increased sensitivity, device simplification, and rapid sensing with multiple capabilities. Depending on the application, biosensors can be fabricated from different materials. TiO₂ is a semiconductor material and has received significant attention for various applications such as sensors, solar cells, water splitting, etc. The wide applicability of recently developed novel composition and structure of TiO₂ materials has accelerated the development and miniaturization of biosensor devices. This study focuses on recent achievements in TiO₂ nanostructured hybrids-based biosensors for detecting various biological markers important for healthcare.

Keywords: Electrochemical sensors; Electrochemistry; Hybrid electrodes; Metal oxides; Nanohybrids; Nanostructures.

Publication types

Review

MeSH terms

Biosensing Techniques / methods*
Electrochemistry / methods*
Nanostructures / chemistry*
Nanotechnology / methods*
Titanium / chemistry*

Substances

titanium dioxide
Titanium