One Hundred Skull Base Meningiomas Operated at Black Lion Specialized Hospital, Addis Ababa, Ethiopia

World Neurosurg. 2019 Jun:126:e1321-e1329. doi: 10.1016/j.wneu.2019.03.088. Epub 2019 Mar 20.

Abstract

Objective: After 10 years of training in their home country, neurosurgeons at Black Lion Specialized Hospital (Addis Ababa, Ethiopia) operated on skull base meningiomas independent of their external teachers. The present study used a retrospective design of an in-hospital series with short-term follow-up.

Methods: A total of 100 patients (mean age, 40.2 years; 80% women) had undergone surgery for skull base meningiomas from 2016 to 2017. Their symptoms included headache in 90%, impairment of vision in 47%, gait impairment in 25%, cognitive dysfunction in 29%, and seizures in 18%. Of the 100 tumors, 44% had a diameter >50 mm. Microsurgery was performed using the Hudson drill, Gigli saw, and conventional microsurgical instruments.

Results: A total of 59 complications in 39 patients occurred. Eleven patients had died within 3 months postoperatively. The cranial infection rate was 14%. The rate of Simpson grade I and II was 63%. We present the 3-12-month outcomes for 84 of the 100 patients. Of the 16 remaining patients, 4 were lost to follow-up (mean, 6.7 months) and 12 had died. Headache was noted in 65 of 74 patients preoperatively and in 20 during follow-up. Overall, 33 patients reported better vision, 48 reported similar vision, and 3 patients reported worse vision. Finally, 20 patients had gait difficulties preoperatively and 9 reported impaired gait during follow-up.

Conclusion: A young faculty of neurosurgeons in a low income country was trained to perform neurosurgery for skull base meningiomas. The patients had presented at a young age with severe disabilities due to advanced disease. Surgery led to symptom improvement in a large proportion of patients; however, the complication and mortality rates were high.

Keywords: Ethiopia; Meningioma; Outcomes; Skull base; Surgery.

MeSH terms

  • Adult
  • Ethiopia
  • Female
  • Humans
  • Male
  • Meningeal Neoplasms / surgery*
  • Meningioma / surgery*
  • Middle Aged
  • Neurosurgical Procedures / adverse effects
  • Neurosurgical Procedures / methods
  • Postoperative Complications / epidemiology*
  • Retrospective Studies
  • Skull Base Neoplasms / surgery*
  • Treatment Outcome