Craving for Introns

Michela Zaffagni; Sebastian Kadener

doi:10.1016/j.molcel.2019.03.008

Craving for Introns

Mol Cell. 2019 Mar 21;73(6):1095-1096. doi: 10.1016/j.molcel.2019.03.008.

Authors

Michela Zaffagni¹, Sebastian Kadener²

Affiliations

¹ Department of Biology, Brandeis University, 415 South Street, Waltham, MA 02453, USA.
² Department of Biology, Brandeis University, 415 South Street, Waltham, MA 02453, USA. Electronic address: skadener@brandeis.edu.

PMID: 30901563
DOI: 10.1016/j.molcel.2019.03.008

Abstract

Parenteau et al. (2019) and Morgan et al. (2019) showed that a subset of introns can work as non-coding RNAs that trap the spliceosome and decrease global splicing upon nutrient depletion in yeast, providing a new example of the functionality of introns, molecules that were previously assumed to be useless.

Publication types

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MeSH terms

Introns*
RNA Splicing*
Saccharomyces cerevisiae
Spliceosomes*