Metastatic mixed adenoneuroendocrine carcinoma of the liver successfully resected by hepatic trisectionectomy following chemotherapy: A case report

Osamu Sato; Takahiro Tsuchikawa; Toru Yamada; Daisuke Sato; Yoshitsugu Nakanishi; Toshimichi Asano; Takehiro Noji; Kurashima Yo; Yuma Ebihara; Soichi Murakami; Toru Nakamura; Keisuke Okamura; Toshiaki Shichinohe; Tomoko Mitsuhashi; Satoshi Hirano

doi:10.1002/ccr3.1968

Metastatic mixed adenoneuroendocrine carcinoma of the liver successfully resected by hepatic trisectionectomy following chemotherapy: A case report

Clin Case Rep. 2019 Feb 1;7(3):491-496. doi: 10.1002/ccr3.1968. eCollection 2019 Mar.

Authors

Osamu Sato¹, Takahiro Tsuchikawa¹, Toru Yamada^{1

2}, Daisuke Sato^{1

2}, Yoshitsugu Nakanishi¹, Toshimichi Asano¹, Takehiro Noji¹, Kurashima Yo¹, Yuma Ebihara¹, Soichi Murakami¹, Toru Nakamura¹, Keisuke Okamura¹, Toshiaki Shichinohe¹, Tomoko Mitsuhashi², Satoshi Hirano¹

Affiliations

¹ Department of Gastroenterological Surgery II Hokkaido University Faculty of Medicine Sapporo Japan.
² Department of Surgical Pathology Hokkaido University Hospital Sapporo Japan.

Abstract

The chemotherapy guidelines for mixed adenoneuroendocrine carcinoma (MANEC) remain poorly defined, and prognosis remains dismal. In this case, we successfully performed resection after FOLFOX for unresectable metastatic MANEC of the liver. Thus, chemotherapy for adenocarcinoma may be effective for MANEC.

Keywords: immunohistochemistry; mixed adenoneuroendocrine carcinoma; neuroendocrine carcinoma; neuroendocrine tumor.

Publication types

Case Reports