[Medical prevention and treatment of radiation-induced urological and nephrological complications]

Cancer Radiother. 2019 Apr;23(2):151-160. doi: 10.1016/j.canrad.2018.05.007. Epub 2019 Mar 18.
[Article in French]

Abstract

Abdominal and pelvic irradiations play a major place in the management of patients with cancer and present a risk of acute and late side effects. Radiation-induced lesions can affect kidney or urological structures. These side effects can have an impact in the quality of life of patients. The aim of this article is to describe the physiopathology, the symptomatology, and the principles of management of radiation-induced nephropathy, uretheritis, cystitis, and urethritis.

Keywords: Cystite radique; Effets secondaires; Néphropathie radique; Physiopathologie; Physiopathology; Radiation-induced cystitis; Radiation-induced nephropathy; Radiation-induced uretheritis; Radiation-induced urethritis; Radiotherapy; Radiothérapie; Side effects; Toxicity; Toxicité; Urétrite radique; Urétérite radique.

Publication types

  • Review

MeSH terms

  • Antioxidants / therapeutic use
  • Estrogens, Conjugated (USP) / administration & dosage
  • Humans
  • Immunologic Factors / administration & dosage
  • Laser Therapy
  • Myoblasts / transplantation
  • Neoplasms / radiotherapy
  • Polydeoxyribonucleotides / administration & dosage
  • Radiotherapy / adverse effects*
  • Urologic Diseases / etiology*
  • Urologic Diseases / therapy*
  • Vascular Endothelial Growth Factor A / administration & dosage

Substances

  • Antioxidants
  • Estrogens, Conjugated (USP)
  • Immunologic Factors
  • Polydeoxyribonucleotides
  • Vascular Endothelial Growth Factor A