Brain-Computer Interfaces in Quadriplegic Patients

Morgan B Lee; Daniel R Kramer; Terrance Peng; Michael F Barbaro; Charles Y Liu; Spencer Kellis; Brian Lee

doi:10.1016/j.nec.2018.12.009

Brain-Computer Interfaces in Quadriplegic Patients

Neurosurg Clin N Am. 2019 Apr;30(2):275-281. doi: 10.1016/j.nec.2018.12.009. Epub 2019 Feb 18.

Authors

Morgan B Lee¹, Daniel R Kramer², Terrance Peng², Michael F Barbaro², Charles Y Liu², Spencer Kellis², Brian Lee³

Affiliations

¹ Department of Neurological Surgery, Keck School of Medicine of USC, University of Southern California, 1200 North State Street, Suite 3300, Los Angeles, CA 90033, USA; USC Neurorestoration Center, Keck School of Medicine of USC, University of Southern California, 1975 Zonal Ave, Los Angeles, CA 90033, USA; T&C Chen Brain Machine Interface Center, California Institute of Technology, 1200 E California Boulevard, Pasadena, CA 91125, USA. Electronic address: morganle@usc.edu.
² Department of Neurological Surgery, Keck School of Medicine of USC, University of Southern California, 1200 North State Street, Suite 3300, Los Angeles, CA 90033, USA; USC Neurorestoration Center, Keck School of Medicine of USC, University of Southern California, 1975 Zonal Ave, Los Angeles, CA 90033, USA; T&C Chen Brain Machine Interface Center, California Institute of Technology, 1200 E California Boulevard, Pasadena, CA 91125, USA.
³ Department of Neurological Surgery, Keck School of Medicine of USC, University of Southern California, 1200 North State Street, Suite 3300, Los Angeles, CA 90033, USA; USC Neurorestoration Center, Keck School of Medicine of USC, University of Southern California, 1975 Zonal Ave, Los Angeles, CA 90033, USA; T&C Chen Brain Machine Interface Center, California Institute of Technology, 1200 E California Boulevard, Pasadena, CA 91125, USA; Department of Biology and Biological Engineering, California Institute of Technology, 1200 E California Boulevard, Pasadena, CA 91125, USA.

PMID: 30898278
DOI: 10.1016/j.nec.2018.12.009

Abstract

Brain-computer interfaces (BCI) are implantable devices that interface directly with the nervous system. BCI for quadriplegic patients restore function by reading motor intent from the brain and use the signal to control physical, virtual, and native prosthetic effectors. Future closed-loop motor BCI will incorporate sensory feedback to provide patients with an effective and intuitive experience. Development of widely available BCI for patients with neurologic injury will depend on the successes of today's clinical BCI. BCI are an exciting next step in the frontier of neuromodulation.

Keywords: Brain-computer interfaces (BCI); Brain-machine interfaces (BMI); Functional electrical stimulation (FES); Neuromodulation.

Publication types

Review

MeSH terms

Brain / physiopathology*
Brain-Computer Interfaces*
Humans
Quadriplegia / physiopathology
Quadriplegia / rehabilitation*