Allograft or autograft in skeletally immature anterior cruciate ligament reconstruction: a prospective evaluation using both partial and complete transphyseal techniques

J Orthop Surg Res. 2019 Mar 21;14(1):85. doi: 10.1186/s13018-019-1128-7.

Abstract

Objective: We compared autografts and allograft using partial and complete transphyseal anterior cruciate ligament (ACL) reconstruction techniques among skeletally immature individuals.

Methods: Male and females younger than 18 and 16 years old, respectively, diagnosed with ACL tear from April 2006 to March 2012 entered the study. One group had four-strand hamstring autograft, and the other had tibialis posterior allograft reconstruction. Those who had allografts either had hyper-laxity or recurvatum.

Results: Achieved mean (± SD) 2000 International Knee Documentation Committee subjective score was not statistically different (P = 0.385) between allograft (n = 13) (84.3 ± 3.2) and autograft groups (n = 18) (85.6 ± 4.4). Mean Knee injury and Osteoarthritis Outcome Score (KOOS) subscale Knee-Related Quality of Life at 2 years was 78.0 ± 7.2 and 75 ± 7.4 for allograft and autograft groups, respectively (p = 0.261). Mean 2-year KOOS subscale Sports and Recreation was 82.1 ± 5.8 and 84.8 ± 6.6 for allograft and autograft groups, respectively (p = 0.244). No patient reported instability, giving way, or locking of the knee. Pivot shift test was negative in all patients; however, a minor positive Lachman test was found in six cases (46%) within the allograft group and seven cases (39%) in the autograft group. One postoperative septic arthritis was documented in the autograft group.

Conclusion: Considering existing concern that joint laxity and recurvatum are among the precursors of non-contact ACL injury in adolescents, bone-patellar-bone autografts are not applicable in this age group because of the open physis; furthermore, considering that hamstring autografts are insufficient (size thickness and stretchability), we recommend soft tissue allografts for ACL reconstruction in skeletally immature patients.

Keywords: Adolescent; Allograft; Anterior cruciate ligament; Autograft; Reconstruction.

MeSH terms

  • Adolescent
  • Anterior Cruciate Ligament Injuries / diagnostic imaging*
  • Anterior Cruciate Ligament Injuries / epidemiology
  • Anterior Cruciate Ligament Injuries / surgery*
  • Anterior Cruciate Ligament Reconstruction / methods*
  • Anterior Cruciate Ligament Reconstruction / trends
  • Autografts / diagnostic imaging
  • Autografts / transplantation*
  • Female
  • Follow-Up Studies
  • Humans
  • Joint Instability / diagnostic imaging*
  • Joint Instability / epidemiology
  • Male
  • Postoperative Care / methods
  • Postoperative Care / trends
  • Prospective Studies
  • Transplantation, Autologous / methods
  • Transplantation, Autologous / trends
  • Transplantation, Homologous / methods
  • Transplantation, Homologous / trends