Implementation of an evidence-based practice to decrease surgical site infection after coronary artery bypass grafting

J Int Med Res. 2019 Aug;47(8):3491-3501. doi: 10.1177/0300060519836511. Epub 2019 Mar 21.

Abstract

Objective: Surgical site infection (SSI) is a serious complication after coronary artery bypass grafting (CABG). This study was performed to evaluate evidence-based practice and structured problem-solving to reduce SSI after CABG.

Methods: An infection control strategy including supervised chlorhexidine gluconate (CHG) showers was implemented from January 2017 to March 2018 for 119 patients undergoing CABG. The controls comprised 244 patients who underwent CABG from 2014 to 2016. Risk factors for SSI were identified, and a problem-focused strategy was used to control SSI. Propensity score matching was used to study the effect of CHG showers on SSI.

Results: SSI occurred in 25 patients (10.25%) in the control group, and the significant risk factors were the postoperative blood glucose level, transfer from an outside hospital, emergency operation, redo sternotomy, a higher American Society of Anesthesiologists score, and the duration of surgery. After implementation of the program, the SSI rate significantly decreased to 3.36%. Patients who had undergone preoperative CHG showers had a significantly lower SSI rate (1.69%) than the matched controls (13.56%).

Conclusion: SSI after CABG can be reduced using evidence-based practice and structured problem-solving to identify risk factors. A preoperative CHG shower is associated with a lower SSI rate after CABG.

Keywords: Surgical site infection; chlorhexidine gluconate; coronary artery bypass grafting; evidence-based practice; infection control; propensity score matching.

MeSH terms

  • Anti-Infective Agents, Local / therapeutic use*
  • Case-Control Studies
  • Chlorhexidine / analogs & derivatives*
  • Chlorhexidine / therapeutic use
  • Coronary Artery Bypass / adverse effects*
  • Coronary Artery Disease / surgery*
  • Evidence-Based Practice / statistics & numerical data*
  • Female
  • Follow-Up Studies
  • Health Plan Implementation*
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Prospective Studies
  • Surgical Wound Infection / drug therapy*
  • Surgical Wound Infection / etiology

Substances

  • Anti-Infective Agents, Local
  • chlorhexidine gluconate
  • Chlorhexidine