Objective: To investigate the association between sleep duration and brachial-ankle pulse wave velocity (baPWV). Methods: A cross-sectional study method was used to observe 38 604 employees of Kailuan Group who participated in the physical examination and the baPWV test from January 2010 to July 2018. The age was (51.6±11.1) years old. There were 72.4% (27 955/38 604) male participants. According to the sleep duration, subjects were divided into 5 groups including ≤ 5 hours group (3 762 cases),>5 hours and ≤6 hours group (9 585 cases),>6 hours and ≤7 hours group (12 604 cases), >7 hours and ≤8 hours group (11 921 cases) and >8 hours group (732 cases). Multivariate logistic regression model was used to analyze the association between sleep duration and the baPWV. Results: The age was (51.6±11.1) years old. There were 72.4% (27 955/38 604) male participants. The prevalence of baPWV≥14 m/s in ≤ 5 hours group, >5 hours and ≤6 hours group, >6 hours and ≤7 hours group, >7 hours and ≤8 hours group, and >8 hours group was 63.5% (2 389/3 762), 58.9% (5 645/9 585), 55.0% (6 926/12 604), 53.3% (6 356/11 921) and 54.8% (401/732) respectively. After adjusting for confounding factors including age, gender, smoking, drinking, physical exercise, snoring, hypertension, diabetes mellitus, dyslipidemia, body mass index≥24 kg/m(2), mean arterial pressure, heart rate, and C-reactive protein, the multivariate logistic regression analysis showed that the OR were 1.48 (95%CI 1.29-1.70, P<0.01) and 1.18 (95%CI 1.07-1.30, P<0.01) respectively for baPWV≥14 m/s in ≤ 5 hours and >5 hours and ≤6 hours group when compared with >7 hours and ≤ 8 hours group. Conclusion: Short sleep duration is associated with elevated baPWV in mid-aged Chinese population.
目的： 探讨夜间睡眠时间与臂踝动脉脉搏波传导速度（baPWV）的关系。 方法： 采用横断面研究方法，以参加2010年1月至2018年7月健康体检且参加baPWV检测的38 604名开滦集团职工作为研究对象。按照夜间睡眠时间，将研究对象分为5组，分别为≤5 h组（3 762名）、>5 h且≤6 h组（9 585名）、>6 h且≤7 h组（12 604名）、>7 h且≤8 h组（11 921名）和>8 h组（732名）。采用多因素logistic回归分析睡眠时间与baPWV≥14 m/s的关系。 结果： 观察对象年龄（51.6±11.1）岁，男性占72.4%（27 955/38 604）。≤5 h组、>5 h且≤6 h组、>6 h且≤7 h组、>7 h且≤8 h组和>8 h组baPWV≥14 m/s的比例分别为63.5%（2 389/3 762）、58.9%（5 645/9 585）、55.0%（6 926/12 604）、53.3%（6 356/11 921）和54.8%（401/732）。多因素logistic回归分析显示，校正年龄、性别、吸烟、饮酒、体育锻炼、打鼾、高血压、糖尿病、血脂异常、体重指数≥24 kg/m(2)、平均动脉压、心率、C反应蛋白后，与>7 h且≤8 h组比较，≤5 h组和>5 h且≤6 h组观察对象baPWV≥14 m/s的OR值分别为1.48（95%CI 1.29~1.70，P<0.01）和1.18（95%CI 1.07~1.30，P<0.01）。 结论： 短夜间睡眠时间与baPWV升高有关。.
Keywords: Pulse wave velocity; Sleep.