RF magnetron sputtering mediated NiTi/Ag coating on Ti-alloy substrate with enhanced biocompatibility and durability

Elangovan Thangavel; Vishnu Shankar Dhandapani; Karthigaimuthu Dharmalingam; Mohana Marimuthu; Murugan Veerapandian; Madhan Kumar Arumugam; Sanghyo Kim; Byungki Kim; Subramaniyan Ramasundaram; Dae-Eun Kim

doi:10.1016/j.msec.2019.01.099

RF magnetron sputtering mediated NiTi/Ag coating on Ti-alloy substrate with enhanced biocompatibility and durability

Mater Sci Eng C Mater Biol Appl. 2019 Jun:99:304-314. doi: 10.1016/j.msec.2019.01.099. Epub 2019 Jan 23.

Affiliations

¹ Department of Energy Studies, Periyar University, Salem 636 011, Tamil Nadu, India. Electronic address: elangoes@periyaruniversity.ac.in.
² Department of Mechanical Engineering, Yonsei University, Seoul 03722, Republic of Korea; PG & Research Department of Physics, PSG College of Arts & Science, Coimbatore 641 014, Tamil Nadu, India.
³ Department of Energy Studies, Periyar University, Salem 636 011, Tamil Nadu, India.
⁴ Department of Biotechnology, Alagappa University, Science Campus, Karaikudi 630 003, Tamil Nadu, India; College of BioNanotechnology, Gachon University, Seongnam 461-701, Republic of Korea.
⁵ Electrodics and Electrocatalysis Division, CSIR-Central Electrochemical Research Institute, Karaikudi 630 003, Tamil Nadu, India.
⁶ Center of Research Excellence in Corrosion, Research Institute, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia.
⁷ College of BioNanotechnology, Gachon University, Seongnam 461-701, Republic of Korea.
⁸ School of Mechatronics Engineering, Korea University of Technology and Education, Chungnam 31253, South Korea.
⁹ School of Mechatronics Engineering, Korea University of Technology and Education, Chungnam 31253, South Korea; Deapartemnt of Chemistry, Karunya Institute of Technology and Sciences, Karunya University, Coimbatore 641114, Tamil Nadu, India.
¹⁰ Department of Mechanical Engineering, Yonsei University, Seoul 03722, Republic of Korea.

PMID: 30889704
DOI: 10.1016/j.msec.2019.01.099

Abstract

Mechanically robust, biocompatible and corrosion resistant Ag doped NiTi (NiTi/Ag) coatings were formed on implant grade commercially pure titanium substrates by R.F. magnetron sputtering. Five samples with varying silver content (0, 1, 3, 7, and 10 at.%) were prepared by controlling the power applied to Ag and NiTi targets. The intensity of X-ray photoelectron spectra peaks corresponding to Ni2p, Ti2p, Ag3d components were found proportional to respective coating compositions. The soft Ag crystallites were decreased the roughness and crystallinity of NiTi/Ag. Among all compositions, NiTi/Ag coating with 3 at.% Ag exhibited lowest friction coefficient (0.1) and wear rate (0.69 × 10^-07 mm³/N ∗ mm). Electrochemical corrosion measurements indicated that Ag incorporation increased the corrosion resistance of NiTi. Increase in Ag content shifted E_corr values in the anodic direction, and reduced the current density by one-order-of-magnitude. When cultured on NiTi/Ag coating with 3 at.% Ag, human dermal fibroblast neonatal cells demonstrated highest cell viability. The fluorescence micrographic image of the immunostained cells showed a well grown actin filament network. Overall, NiTi/Ag coated titanium substrates were found to be a promising orthopedic implant material.

Keywords: Biocompatibility; Cell viability; Durability; NiTi/Ag; R.F sputtering; Wear rate.

MeSH terms

Alloys / pharmacology*
Coated Materials, Biocompatible / pharmacology*
Corrosion
Dermis / cytology
Electric Impedance
Electrochemical Techniques
Fibroblasts / cytology
Fibroblasts / drug effects
Friction
Humans
Materials Testing / methods*
Microscopy, Atomic Force
Photoelectron Spectroscopy
Radio Waves*
Silver / pharmacology*
Surface Properties
Titanium / pharmacology*

Substances

Alloys
Coated Materials, Biocompatible
nitinol
Silver
Titanium