Public hospitalizations for stroke in Brazil from 2009 to 2016

PLoS One. 2019 Mar 19;14(3):e0213837. doi: 10.1371/journal.pone.0213837. eCollection 2019.

Abstract

Background: Stroke is the third major cause of death in the world and the second in Brazil. The purpose of this work was to assess the stroke-related hospitalization, in-hospital mortality, and case fatality rates under the Brazilian Unified Health System (SUS) from 2009 to 2016.

Methods: We evaluated the hospital admissions for stroke and their associated outcomes using data from the Hospital Information available at the Informatics Department of SUS. We selected hospitalization registries according to stroke diagnosis codes from the International Statistical Classification of Diseases and Related Health Problems (ICD-10). We identified the association of age and sex with patient death through multiple logistic regression and calculated the rates of hospitalization, mortality and case-fatality per 100,000 inhabitants using age-adjustment methodology.

Results: We analyzed 1,113,599 stroke hospitalizations. From 2009 to 2016, the number of admissions increased from 131,122 to 146,950 and the absolute number of in-hospital deaths increased from 28,731 to 31,937. Younger age and male sex were significantly associated with patient survival. Our results showed that the annual age-adjusted hospitalization and in-hospital mortality rates decreased by 11.8% and 12.6%, respectively, but the case fatality rate increased for patients older than 70 years.

Conclusions: Although the age-adjusted hospitalization and in-hospital mortality rates declined, the total number of hospitalization and deaths have increased. It is expected a continuous increase over the next years of stroke admissions with the rapid aging of the Brazilian population. Efforts should be renewed targeting risk factors, access to hospital and rehabilitation in particular for the elderly population.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Brazil / epidemiology
  • Female
  • Hospital Mortality
  • Hospitalization / statistics & numerical data*
  • Hospitals, Public
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Sex Factors
  • Stroke / diagnosis*
  • Stroke / epidemiology
  • Stroke / mortality
  • Survival Rate
  • Young Adult

Grants and funding

This work was supported by the National Council for Scientific and Technological Development (CNPq) http://cnpq.br/ [grant numbers 306802/2015-5 and 403863/2016-3 to SH; 140511/2018-0 to RAQN; 169049/2017-5 to LFD]; Carlos Chagas Filho Foundation (FAPERJ) http://www.faperj.br/ [grant number E-26/201.959/2017 to JFM]; the Coordination for the Improvement of Higher Education Personnel (CAPES) http://www.capes.gov.br/; and the Pontifical Catholic University of Rio de Janeiro http://www.puc-rio.br/english/. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.