Electrochemical sensing of nicotine using CuWO4 decorated reduced graphene oxide immobilized glassy carbon electrode

A Karthika; P Karuppasamy; S Selvarajan; A Suganthi; M Rajarajan

doi:10.1016/j.ultsonch.2019.01.038

Electrochemical sensing of nicotine using CuWO₄ decorated reduced graphene oxide immobilized glassy carbon electrode

Ultrason Sonochem. 2019 Jul:55:196-206. doi: 10.1016/j.ultsonch.2019.01.038. Epub 2019 Jan 29.

Authors

A Karthika¹, P Karuppasamy², S Selvarajan¹, A Suganthi³, M Rajarajan⁴

Affiliations

¹ PG & Research Department of Chemistry, Thiagarajar College, Madurai 625009, Tamilnadu, India.
² Anna University Regional Campus - Tirunelveli, Tirunelveli 627007, Tamilnadu, India.
³ PG & Research Department of Chemistry, Thiagarajar College, Madurai 625009, Tamilnadu, India; Mother Teresa Women's University, Kodaikanal 624 102, Tamilnadu, India. Electronic address: suganthiphd09@gmail.com.
⁴ Madurai Kamaraj University, Madurai 625 02, Tamilnadu, India. Electronic address: rajarajan_1962@yahoo.com.

PMID: 30878204
DOI: 10.1016/j.ultsonch.2019.01.038

Abstract

A novel and selective electrochemical sensing of nicotine is studied using copper tungstate decorated reduced graphene oxide nanocomposite (CuWO₄/rGO) nafion (Nf) immobilized GC electrode (GCE). The CuWO₄/rGO nanocomposite is synthesized using sonication method and characterized by HR-TEM (High resolution transmission electron microscopy), SEM (Scanning electron microscopy), FT-IR (Fourier transform infrared spectroscopy), SAED (Selected area of electron diffraction pattern), XRD (X-ray diffraction), Raman spectroscopy, Thermo gravimetric analysis (TGA) and EDX (Energy dispersive X-ray diffraction) techniques. The CuWO₄/rGO/Nf immobilized GCE shows better electrocatalytic response for the detection of nicotine as compared to bare GCE. A better selectivity and sensitivity is achieved using CuWO₄/rGO/Nf immobilized GCE to detect 0.1 µM nicotine in the presence of 100-fold excess concentrations of different interferents. The present CuWO₄/rGO/Nf immobilized GCE electrochemical sensor exhibits an ample range of sensing from 0.1 µM to 0.9 µM and the low detection limit is found to be 0.035 µM (S/N = 3). Comparable results are achieved for the determination of nicotine in various real samples such as cigarettes (Gold flake and Wills) and urine samples with improved recoveries.

Keywords: CuWO(4)/rGO nanocomposite; Electrochemical sensor; Nicotine.

Publication types

Review