Multiple-path interference plays a fundamental role in classical and quantum physics. In this work, we propose two general schemes to realize multiple electromagnetically induced transparency (EIT) and electromagnetically induced absorption (EIA) in coupled microresonators and optomechanical systems. We give explicit physical descriptions and find out that these two schemes are essentially equivalent to each other. More importantly, we experimentally demonstrate both multiple EIT and EIA by coupling a microtoroid to a microsphere that supports multiple high Q optical modes with dense modes distributions. The theory fits well with the experimental results. We believe that our study and experimental results lay a foundation for realizing arbitrary multiple pathways interference in applications.