FoldX 5.0: working with RNA, small molecules and a new graphical interface

Javier Delgado; Leandro G Radusky; Damiano Cianferoni; Luis Serrano

doi:10.1093/bioinformatics/btz184

FoldX 5.0: working with RNA, small molecules and a new graphical interface

Bioinformatics. 2019 Oct 15;35(20):4168-4169. doi: 10.1093/bioinformatics/btz184.

Authors

Javier Delgado¹, Leandro G Radusky¹, Damiano Cianferoni¹, Luis Serrano^{1

2

3}

Affiliations

¹ Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain.
² Universitat Pompeu Fabra (UPF), Barcelona, Spain.
³ Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.

Abstract

Summary: A new version of FoldX, whose main new features allows running classic FoldX commands on structures containing RNA molecules and includes a module that allows parametrization of ligands or small molecules (ParamX) that were not previously recognized in old versions, has been released. An extended FoldX graphical user interface has also being developed (available as a python plugin for the YASARA molecular viewer) allowing user-friendly parametrization of new custom user molecules encoded using JSON format.

Availability and implementation: http://foldxsuite.crg.eu/.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Ligands
RNA
Software*
User-Computer Interface*

Substances

Ligands
RNA