The OSA Topical Meeting on Computational Optical Sensing and Imaging (COSI) was held June 25-June 28, 2018 in Orlando, Florida, USA, as part of the Imaging and Applied Optics Congress. In this feature issue, we present several papers that cover the techniques, topics, and advancements in the field presented at the COSI meeting highlighting the integration of opto-electric measurement and computational processing.