The Associations between Central Nervous System Diseases and Haemostatic Disorders

Maria Podsiedlik; Magdalena Markowicz-Piasecka; Elżbieta Mikiciuk-Olasik; Joanna Sikora

doi:10.2174/1871527318666190314101946

The Associations between Central Nervous System Diseases and Haemostatic Disorders

CNS Neurol Disord Drug Targets. 2019;18(4):307-316. doi: 10.2174/1871527318666190314101946.

Authors

Maria Podsiedlik¹, Magdalena Markowicz-Piasecka², Elżbieta Mikiciuk-Olasik¹, Joanna Sikora²

Affiliations

¹ Department of Pharmaceutical Chemistry, Drug Analysis and Radiopharmacy, Medical University of Lodz, ul. Muszyńskiego 1, 90-151 Lodz, Poland.
² Laboratory of Bioanalysis, Department of Pharmaceutical Chemistry, Drug Analysis and Radiopharmacy, Medical University of Lodz, ul. Muszyńskiego 1, 90-151 Lodz, Poland.

PMID: 30868969
DOI: 10.2174/1871527318666190314101946

Abstract

The aim of this review was to examine the relationship between the occurrence of central nervous system (CNS) diseases, the medicines used in their treatment and the blood coagulation process. The paper mainly focuses on the effects of antidepressant and antipsychotic drugs. Special attention has been paid to the influence of drugs on platelets, the vascular endothelium, plasma coagulation and fibrinolysis, regarding coagulation.

Keywords: Coagulation; antidepressant drugs; antipsychotic drugs; central nervous system diseases; haemostasis; vascular endothelium..

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Antidepressive Agents / pharmacology*
Antidepressive Agents / therapeutic use
Antipsychotic Agents / pharmacology*
Antipsychotic Agents / therapeutic use
Blood Coagulation / drug effects*
Central Nervous System Diseases / complications
Central Nervous System Diseases / drug therapy*
Hemostatic Disorders / complications*
Humans

Substances

Antidepressive Agents
Antipsychotic Agents