Development of temporal lobe epilepsy during maintenance electroconvulsive therapy: A case of human kindling?

Caroline Schotte; Evy Cleeren; Karolien Goffin; Borbala Hunyadi; Satya Buggenhout; Koen Van Laere; Wim Van Paesschen

doi:10.1002/epi4.12294

Development of temporal lobe epilepsy during maintenance electroconvulsive therapy: A case of human kindling?

Epilepsia Open. 2019 Jan 15;4(1):200-205. doi: 10.1002/epi4.12294. eCollection 2019 Mar.

Authors

Caroline Schotte¹, Evy Cleeren^{1

2}, Karolien Goffin^{3

4}, Borbala Hunyadi^{5

6}, Satya Buggenhout⁷, Koen Van Laere^{3

4}, Wim Van Paesschen^{1

2}

Affiliations

¹ Department of Neurology University Hospitals Leuven Leuven Belgium.
² Laboratory for Epilepsy Research KU Leuven Leuven Belgium.
³ Department of Nuclear Medicine University Hospital Leuven Leuven Belgium.
⁴ Department of Imaging and Pathology Nuclear Medicine and Molecular Imaging KU Leuven Leuven Belgium.
⁵ Faculty of EEMCS TU Delft Delft The Netherlands.
⁶ Department of Electrical Engineering (ESAT) STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics KU Leuven Leuven Belgium.
⁷ Department of Psychiatry University Psychiatric Centre KU Leuven Kortenberg Belgium.

Abstract

We describe a patient with new-onset temporal lobe epilepsy during prolonged maintenance electroconvulsive therapy. We suggest a possible causal relationship with maintenance electroconvulsive therapy through electrical kindling of the temporal lobe.

Keywords: electroconvulsive therapy; kindling; temporal lobe epilepsy.