Measuring the Energetic Costs of Embryonic Development

Peter J Foster; Manuel Razo-Mejia; Rob Phillips

doi:10.1016/j.devcel.2019.02.016

Measuring the Energetic Costs of Embryonic Development

Dev Cell. 2019 Mar 11;48(5):591-592. doi: 10.1016/j.devcel.2019.02.016.

Authors

Peter J Foster¹, Manuel Razo-Mejia², Rob Phillips³

Affiliations

¹ Physics of Living Systems, Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
² Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
³ Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Department of Physics, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: phillips@pboc.caltech.edu.

PMID: 30861370
DOI: 10.1016/j.devcel.2019.02.016

Abstract

What are the thermodynamic costs of development? In this issue of Developmental Cell, Rodenfels et al. (2019) demonstrate that the high energetic cost of coordinated cell division that is regulated by phospho-signaling gives rise to a measurable periodicity in the heat dissipated during zebrafish embryogenesis.

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MeSH terms

Animals
Cell Division
Embryo, Nonmammalian
Embryonic Development
Gene Expression Regulation, Developmental*
Hot Temperature*
Zebrafish / genetics