Food and drug administration - approved molecular methods for detecting human papillomavirus infection

Katarzyna Sitarz; Slawa Szostek

doi:10.5603/GP.2019.0018

Food and drug administration - approved molecular methods for detecting human papillomavirus infection

Ginekol Pol. 2019;90(2):104-108. doi: 10.5603/GP.2019.0018.

Authors

Katarzyna Sitarz^{1

2}, Slawa Szostek³

Affiliations

¹ Department of Virology, Chair of Microbiology, Jagiellonian University Medical College, Cracow, Poland.
² Faculty of Chemistry, Jagiellonian University, Cracow, Poland.
³ Department of Virology, Chair of Microbiology, Jagiellonian University Medical College, Cracow, Poland. slawa.szostek@uj.edu.pl.

PMID: 30860278
DOI: 10.5603/GP.2019.0018

Abstract

In the world, there are many tests that allow the detection of HPV infection. These tests are based on different operating principles and have different levels of sensitivity. The first test to detect HPV infection was approved by the Food and Drug Administration in 2003. Since then, the FDA has approved five more commercial tests for this purpose, the last one in 2018. This paper discusses the principles of molecular tests to detect HPV, which have been approved by the FDA, the main differences between them, as well as their advantages and disadvantages.

Keywords: Aptima; COBAS; Cervista; HPV detection; Hybrid Capture; Onclarity.

Publication types

Review

MeSH terms

Female
Humans
Molecular Diagnostic Techniques*
Papillomaviridae* / genetics
Papillomaviridae* / isolation & purification
Papillomavirus Infections / diagnosis*
United States
United States Food and Drug Administration
Uterine Cervical Neoplasms / prevention & control