Peritonitis by Exophiala dermatitidis in a pediatric patient

Rosângela L Pinheiro; Regielly C R Cognialli; Rodolfo C Barros; Tyane de A Pinto; Mariana F M Cunha; Tony T Tahan; Morgana F Voidaleski; Renata R Gomes; Guilherme N Becker; Lucas V Andrade; Flavio Queiroz-Telles; G Sybren de Hoog; Renata R Sakiyama; Vânia A Vicente

doi:10.1016/j.mmcr.2019.02.001

Peritonitis by Exophiala dermatitidis in a pediatric patient

Med Mycol Case Rep. 2019 Feb 15:24:18-22. doi: 10.1016/j.mmcr.2019.02.001. eCollection 2019 Jun.

Authors

Rosângela L Pinheiro¹, Regielly C R Cognialli¹, Rodolfo C Barros¹, Tyane de A Pinto², Mariana F M Cunha², Tony T Tahan², Morgana F Voidaleski³, Renata R Gomes³, Guilherme N Becker⁴, Lucas V Andrade⁵, Flavio Queiroz-Telles^{1

3}, G Sybren de Hoog^{3

6

7

8}, Renata R Sakiyama², Vânia A Vicente³

Affiliations

¹ Laboratory of Mycology, Clinical Analysis Service Unit, Clinical Hospital Complex, Federal University of Paraná Curitiba, PR, Brazil.
² Department of Pediatrics, Pediatric Infectiology Service, Hospital Clinic Complex, Federal University of Paraná, Curitiba, PR, Brazil.
³ Microbiology, Parasitology and Pathology Post-graduation Program, Department of Basic Pathology, Federal University of Paraná, Curitiba, PR, Brazil.
⁴ Bacteriology Division, Central Laboratory of Paraná State, São José dos Pinhais, PR, Brazil.
⁵ Medical College of the União das Faculdades dos Grandes Lagos, São José do Rio Preto, SP, Brazil.
⁶ Westerdijk Fungal Biodiversity Institute, Utrecht, the Netherlands.
⁷ Centre of Expertise in Mycology of Radboud University Medical Centre / Canisius Wilhelmina Hospital, Nijmegen, the Netherlands.
⁸ Department of Dermatology and Venereology, Union Hospital, Tongji Medical College, Huazhong Science and Technology University, Jiefang Dadao 1277, Wuhan, Hubei, China.

Abstract

Fungal peritonitis is frequent on peritoneal dialysis, with rare cases by Exophiala dermatitidis. A 25-month-old female admitted to the pediatric ICU with acute renal failure was submitted to peritoneal dialysis. After 10 days patient presented fever. Peritoneal fluid culture showed yeast colonies molecularly identified as E. dermatitidis. Patient was treated with voriconazole and hemodialysis. The literature was reviewed. Disseminated infections are frequently fatal, but appropriate diagnose and therapeutic led to cure in this case.

Keywords: Dialysis; Fungal infection; Molecular diagnosis; Phaeohyphomycosis; Therapeutic management.

Publication types

Case Reports