CT dosimetry at the Australian Synchrotron for 25-100 keV photons and 35-160 mm-diameter biological specimens

J Synchrotron Radiat. 2019 Mar 1;26(Pt 2):517-527. doi: 10.1107/S1600577518018015. Epub 2019 Feb 15.

Abstract

The dose length product (DLP) method for medical computed tomography (CT) dosimetry is applied on the Australian Synchrotron Imaging and Medical Beamline (IMBL). Beam quality is assessed from copper transmission measurements using image receptors, finding near 100% (20 keV), 3.3% (25 keV) and 0.5% (30-40 keV) relative contributions from third-harmonic radiation. The flat-panel-array medical image receptor is found to have a non-linear dose response curve. The amount of radiation delivered during an axial CT scan is measured as the dose in air alone, and inside cylindrical PMMA phantoms with diameters 35-160 mm for mono-energetic radiation 25-100 keV. The radiation output rate for the IMBL is comparable with that used for medical CT. Results are presented as the ratios of CT dose indices (CTDI) inside phantoms to in air with no phantom. Ratios are compared for the IMBL against medical CT where bow-tie filters shape the beam profile to reduce the absorbed dose to surface organs. CTDI ratios scale measurements in air to estimate the volumetric CTDI representing the average dose per unit length, and the dose length product representing the absorbed dose to the scanned volume. Medical CT dose calculators use the DLP, beam quality, axial collimation and helical pitch to estimate organ doses and the effective dose. The effective dose per unit DLP for medical CT is presented as a function of body region, beam energy and sample sizes from neonate to adult.

Keywords: Australian Synchrotron Imaging and Medical Beamline; CT dose indices; CT dose length product; CT dosimetry; effective dose; third harmonic.

MeSH terms

  • Australia
  • Humans
  • Phantoms, Imaging
  • Radiation Dosage*
  • Radiometry / methods*
  • Synchrotrons*
  • Tomography Scanners, X-Ray Computed
  • Tomography, X-Ray Computed*