In a cohort of 480 patients admitted to an acute care hospital, 68 (14%) had positive perirectal cultures for toxigenic Clostridioides difficile on admission. Of the 11 patients (2%) diagnosed with healthcare-associated C. difficile infections, 3 (27%) had genetically related admission and infection isolates, based on whole-genome sequencing.
Keywords: Clostridioides difficile; colonization; healthcare-associated; infection control; whole genome sequencing.
Published by Oxford University Press for the Infectious Diseases Society of America 2019.