Minimally Invasive Surgical Approaches for Peritoneal Surface Malignancy

Laura M Enomoto; Edward A Levine; Kathleen C Perry; Konstantinos I Votanopoulos; Michael Kuncewitch; Perry Shen

doi:10.1016/j.soc.2018.11.010

Minimally Invasive Surgical Approaches for Peritoneal Surface Malignancy

Surg Oncol Clin N Am. 2019 Apr;28(2):161-176. doi: 10.1016/j.soc.2018.11.010. Epub 2019 Jan 11.

Authors

Laura M Enomoto¹, Edward A Levine¹, Kathleen C Perry¹, Konstantinos I Votanopoulos¹, Michael Kuncewitch¹, Perry Shen²

Affiliations

¹ Department of Surgery, Wake Forest Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USA.
² Department of Surgery, Wake Forest Baptist Medical Center, Medical Center Boulevard, Winston Salem, NC 27157, USA. Electronic address: pshen@wakehealth.edu.

PMID: 30851821
DOI: 10.1016/j.soc.2018.11.010

Abstract

Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is an evolving strategy in the locoregional management of peritoneal surface malignancies, and the role of laparoscopy is expanding. Staging laparoscopy is routinely used to obtain tissue for diagnosis and assess extent of tumor burden. Laparoscopic CRS and HIPEC with curative intent is safe and effective in patients with a low disease burden. In patients with refractory malignant ascites, complete resolution of ascites and improvement in quality of life have been demonstrated with palliative laparoscopic HIPEC. Laparoscopic CRS and HIPEC has an expanding role in the treatment of peritoneal surface disease.

Keywords: Hyperthermic intraperitoneal chemotherapy; Laparoscopic cytoreductive surgery; Peritoneal carcinomatosis; Peritoneal surface malignancy; Refractory malignant ascites; Staging laparoscopy.

Publication types

Review

MeSH terms

Humans
Hyperthermia, Induced / methods*
Laparoscopy / methods*
Peritoneal Neoplasms / therapy*