Rare benign tumor of the larynx - laryngeal amyloidosis

Rom J Morphol Embryol. 2018;59(4):1263-1268.

Abstract

We report a case of rare benign tumor of the larynx - amyloidosis of larynx - in a 52-year-old female who presented to the Department of Ear, Nose and Throat (ENT), Timişoara Municipal Hospital, Romania, with dysphonia. The patient's first presentation was in June 2012, with a polypoid formation localized on left vocal cord. The patient underwent a suspended microlaryngoscopy (SM) with tumor removal followed by histopathological examination, which revealed a laryngeal amyloidosis. The tumor recurred in 2013, 2014, 2016, 2017 and 2018. The patient underwent tracheotomy, followed by SM with endoscopic CO2 laser procedures, in order to remove the tumor and to ensure the airway. The follow-up was for six years. In May 2018, amyloid was located in subglottis, glottis and left false vocal fold. The patient needed five revision surgical procedures. The patient did not developed systemic amyloidosis during the follow-up period.

Publication types

  • Case Reports

MeSH terms

  • Amyloidosis / pathology*
  • Arterioles / pathology
  • Female
  • Humans
  • Laryngeal Neoplasms / blood supply
  • Laryngeal Neoplasms / pathology*
  • Laryngeal Neoplasms / surgery
  • Larynx / blood supply
  • Larynx / pathology*
  • Middle Aged
  • Stromal Cells / pathology
  • T-Lymphocytes / pathology