Adamantinoma

Excerpt

Adamantinomas are rare, low-grade malignant bone tumors of uncertain histogenesis that predominately affect the diaphyses and metaphyses of the tibia. The tumor is called adamantinoma due to its histological similarity to ameloblastoma, often found in the mandible. Histopathologically, adamantinoma displays biphasic patterns consisting of epithelial cells and osteofibrous components.

There are 2 types of adamantinomas—classical and differentiated—and the latter resembles osteofibrous dysplasia. Despite advancements in imaging techniques, the definitive diagnosis of adamantinoma primarily relies on histopathological examination.