Impact of Physical Function on 1-Year Kidney Transplant Outcomes

West J Nurs Res. 2020 Jan;42(1):50-56. doi: 10.1177/0193945919834889. Epub 2019 Mar 6.

Abstract

End-stage renal disease patients who have impaired physical function are denied for transplantation by clinicians concerned about graft/survival outcomes. The purpose of this study was to determine the impact of physical function on graft/survival outcomes at 1-year post-kidney transplantation. Data were analyzed from the Scientific Registry of Transplant Recipients regarding kidney transplantation patients (N = 218,657) between January 1, 2000 and September 2, 2014. The hazard ratio of 1-year graft failure for deceased donor transplantation recipients needing total assistance was 1.60 (95% confidence interval [CI] = [1.303, 1.965], p < .01). Patients needing none or some assistance did not demonstrate a significant difference in 1-year graft failure in either deceased or living donor transplantation. The hazard ratio of 1-year death for those needing total assistance was 2.52 (95% CI = [2.087, 3.045], p < .001) in deceased donor kidney transplantation.

Keywords: 1-year transplant outcomes; kidney transplant; physical function.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Correlation of Data
  • Exercise / physiology*
  • Female
  • Graft Survival
  • Humans
  • Kaplan-Meier Estimate
  • Kidney Failure, Chronic / complications
  • Kidney Failure, Chronic / therapy*
  • Kidney Transplantation / adverse effects
  • Kidney Transplantation / methods
  • Kidney Transplantation / standards*
  • Male
  • Middle Aged
  • Treatment Outcome
  • United States