Clay-Na as a sorbent for the extraction of anti-inflammatory compounds in water samples

Abstract

In this work, clay-Na particles are used as the adsorbent for the solid-phase extraction of acidic compounds. The novel sorbent under study is based on high-specific surface area, cation-exchange capacity designed specifically to offer ion-exchange properties with the goal being to selectively extract a group of acidic compounds. The effects of the extraction parameters including extraction elution solvent, sample volume and pH. In optimum conditions, the repeatability for one fiber (n = 3), expressed as % relative standard deviation, was between 0.3 and 4.3% for the acid compounds. The detection limits for the studied acidic compounds were between 0.1-0.6 μg/L. The developed method offers the advantages of being simple to use and having a low cost of equipment.

Keywords: anti-inflammatory compounds; clay-Na; high-performance liquid chromatography; solid-phase extraction.