Minimal Clinically Important Difference for UPDRS-III in Daily Practice

Mov Disord Clin Pract. 2018 Jun 26;5(4):448-450. doi: 10.1002/mdc3.12632. eCollection 2018 Jul-Aug.

Álvaro Sánchez-Ferro^{1

2

3

4}, Michele Matarazzo^{1

2

3

5}, Pablo Martínez-Martín^{3

6}, Jose Carlos Martínez-Ávila⁷, Agustín Gómez de la Cámara⁷, Luca Giancardo^{4

8}, Teresa Arroyo Gallego^{9

10

11}, Paloma Montero^{2

12}, Verónica Puertas-Martín², Ignacio Obeso¹, Ian Butterworth⁴, Carlos S Mendoza⁴, Maria José Catalán¹², José Antonio Molina², Félix Bermejo-Pareja², Juan Carlos Martínez-Castrillo¹³, Lydia López-Manzanares¹⁴, Araceli Alonso-Cánovas¹³, Jaime Herreros Rodríguez¹⁵, Martha Gray^{4

10}

¹ HM-CINAC, Hospital Universitario HM Puerta del Sur, Móstoles and Medical School CEU-San Pablo University Madrid Spain.
² Neurology Department Instituto de Investigación del Hospital 12 de Octubre Madrid Spain.
³ Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED) Madrid Spain.
⁴ Research Laboratory of Electronics Massachusetts Institute of Technology Cambridge Massachusetts USA.
⁵ Pacific Parkinson's Research Centre The University of British Columbia Vancouver BC Canada.
⁶ Area of Applied Epidemiology, National Centre of Epidemiology Carlos III Institute of Health Madrid Spain.
⁷ Clinical Research Unit, Instituto de Investigación Hospital 12 de Octubre, Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP) Hospital Universitario 12 de Octubre Madrid Spain.
⁸ Center for Precision Health, School of Biomedical Informatics The University of Texas Health Science Center at Houston Houston USA.
⁹ Biomedical Imaging Technologies ETSI Telecomunicación UPM Madrid Spain.
¹⁰ Institute for Medical Engineering and Science Massachusetts Institute of Technology Cambridge MA USA.
¹¹ nQ Medical Cambridge MA USA.
¹² Movement Disorders Unit Hospital Clínico San Carlos Madrid Spain.
¹³ Movement Disorders Unit Hospital Ramón y Cajal Madrid Spain.
¹⁴ Movement disorders unit Hospital de la Princesa Madrid Spain.
¹⁵ Neurology Department Hospital Infanta Leonor Madrid Spain.

No abstract available

Keywords: Drug Monitoring; Minimal Clinically Important Difference; Parkinson Disease; Pragmatic Clinical Trials; Treatment Outcome.