Stem Cells: Muscle Cells Enwrap Escaped Germline Stem Cells in C. elegans

Charlotte A Kelley; Erin J Cram

doi:10.1016/j.cub.2019.01.035

Stem Cells: Muscle Cells Enwrap Escaped Germline Stem Cells in C. elegans

Curr Biol. 2019 Mar 4;29(5):R150-R152. doi: 10.1016/j.cub.2019.01.035.

Authors

Charlotte A Kelley¹, Erin J Cram²

Affiliations

¹ Northeastern University, Department of Biology, Boston, MA 02115, USA.
² Northeastern University, Department of Biology, Boston, MA 02115, USA. Electronic address: E.Cram@northeastern.edu.

PMID: 30836081
DOI: 10.1016/j.cub.2019.01.035

Abstract

Interactions between the distal tip cell and germline stem cells maintain a proliferative pool of mitotic cells in the Caenorhabditis elegans gonad. A new study shows that escaped germline stem cells induce nearby muscle cells to reach out and wrap around them, forming an ectopic niche similar to the native gonadal germ cell niche.

Publication types

Comment

MeSH terms

Animals
Caenorhabditis elegans Proteins*
Caenorhabditis elegans*
Germ Cells
Gonads
Stem Cells

Substances

Caenorhabditis elegans Proteins

Grants and funding

R01 GM110268/GM/NIGMS NIH HHS/United States