[Diffuse leptomeningeal glioneuronal tumor: report of a case]

S S Cai; X Y Liu; Y P Chen; F L Song; C H Ren; W Guo; S Zhang; X F Wang

doi:10.3760/cma.j.issn.0529-5807.2019.03.019

[Diffuse leptomeningeal glioneuronal tumor: report of a case]

Zhonghua Bing Li Xue Za Zhi. 2019 Mar 8;48(3):253-255. doi: 10.3760/cma.j.issn.0529-5807.2019.03.019.

[Article in Chinese]

Authors

S S Cai¹, X Y Liu², Y P Chen², F L Song², C H Ren², W Guo³, S Zhang², X F Wang²

Affiliations

¹ Department of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China (Cai Shanshan is Working on the Department of Pathology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, China).
² Department of Pathology, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China.
³ Department of Radiology, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China.

PMID: 30831658
DOI: 10.3760/cma.j.issn.0529-5807.2019.03.019

Abstract

回顾性分析1例弥漫性软脑膜胶质神经元肿瘤的临床病理和分子遗传学特征。女性患者，19岁。头晕、视物模糊20 d。MRI示右侧桥小脑区、第四脑室，及颅内、脊髓膜多发异常信号，强化明显。组织学呈低级别胶质瘤特征。免疫组织化学示胶质神经元双向分化。分子遗传学提示染色体1p缺失，19q未缺失，KIAA1549-BRAF融合基因阳性。弥漫性软脑膜胶质神经元肿瘤是2016年WHO分类新增加的一种罕见的混合性胶质神经元肿瘤，暂无明确分级，应注意与少突胶质细胞瘤、毛细胞型星形细胞瘤等相鉴别。.