Levetiracetam-Related Mania-Like Symptoms: An Adolescent Case

Clin Neuropharmacol. 2019 May/Jun;42(3):97-98. doi: 10.1097/WNF.0000000000000335.

Abstract

Levetiracetam is an antiepileptic agent that is used for partial and generalized epilepsy. Although it is well tolerated in most cases, behavioral and nonbehavioral adverse effects may be observed. Among behavioral symptoms, depression, hostility, and agitation have been frequently reported. However, mania or mania-like symptoms are relatively rare, especially in children and adolescents. Hereby, we report mania-like symptoms with levetiracetam use in a 15-year-old boy. Mania-like symptoms emerged 3 weeks after starting levetiracetam and disappeared after adding risperidone to ongoing levetiracetam treatment.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anticonvulsants / adverse effects*
  • Bipolar Disorder / chemically induced*
  • Epilepsies, Partial / drug therapy*
  • Humans
  • Levetiracetam / adverse effects*
  • Male
  • Risperidone / therapeutic use

Substances

  • Anticonvulsants
  • Levetiracetam
  • Risperidone