Site preservation grafting after tooth extraction offers improved predictability for alveolar volume maintenance and successful delayed implant treatment. Multiple techniques and materials are used for these procedures, and each possesses relative benefits and challenges for the clinician and patient. In the case reports presented, the patients were treated with minimally invasive open extraction site preservation with dehydrated amnion/chorion membrane (dHACM) at pontic sites and prior to delayed implant therapy. The biologic rationale for material selection will be reviewed.