Chemical compositions of chrysanthemum teas and their anti-inflammatory and antioxidant properties

Yanfang Li; Puyu Yang; Yinghua Luo; Boyan Gao; Jianghao Sun; Weiying Lu; Jie Liu; Pei Chen; Yaqiong Zhang; Liangli Lucy Yu

doi:10.1016/j.foodchem.2019.02.013

Chemical compositions of chrysanthemum teas and their anti-inflammatory and antioxidant properties

Food Chem. 2019 Jul 15:286:8-16. doi: 10.1016/j.foodchem.2019.02.013. Epub 2019 Feb 12.

Authors

Yanfang Li¹, Puyu Yang², Yinghua Luo³, Boyan Gao⁴, Jianghao Sun⁵, Weiying Lu⁶, Jie Liu⁷, Pei Chen⁸, Yaqiong Zhang⁹, Liangli Lucy Yu¹⁰

Affiliations

¹ Institute of Food and Nutraceutical Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China; Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, United States. Electronic address: zoe_li@sjtu.edu.cn.
² Institute of Food and Nutraceutical Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.
³ Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, United States.
⁴ Institute of Food and Nutraceutical Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China; Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, United States. Electronic address: gaoboyan@sjtu.edu.cn.
⁵ Food Composition and Methods Development Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, United States. Electronic address: jianghao.sun@ars.usda.gov.
⁶ Institute of Food and Nutraceutical Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address: weiying.lu@sjtu.edu.cn.
⁷ Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Technology & Business University (BTBU), Beijing 100048, China. Electronic address: liu_jie@btbu.edu.cn.
⁸ Food Composition and Methods Development Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, United States. Electronic address: pei.chen@ars.usda.gov.
⁹ Institute of Food and Nutraceutical Science, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address: yqzhang2006@sjtu.edu.cn.
¹⁰ Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, United States. Electronic address: lyu5@umd.edu.

PMID: 30827670
DOI: 10.1016/j.foodchem.2019.02.013

Abstract

Seventeen commercial chrysanthemum teas (Chrysanthemum morifolium and Coreopsis tinctoria) were extracted with hot-H₂O, and examined and compared to the 75% methanol extracts for their chemical compositions using UPLC/Q-TOF-MS analysis. For the first time, 6, 8-C,C-diglucosylapigenin and eriodicyol-7-O-glucoside were detected in the Snow chrysanthemum, and acetylmarein was detected in HangJu, GongJu and HuaiJu. The extracts were also examined for their radical scavenging and anti-inflammatory activities in vitro. The hot-H₂O extract of Kunlunmiju 1 had the greatest total phenolic content, and relative DPPH and oxygen radical absorbance capacity values of 12.72 mg gallic acid equivalents/g, 105.48 and 1222.50 μmol Trolox equivalents/g, respectively. In addition, all the hot-H₂O extracts suppressed the lipopolysaccharide-induced interleukin-6, IL-1β and cyclooxygenase-2 mRNA expressions, and H₂O₂-induced intracellular reactive oxygen species production in cultured cells. The results from this research may be used to promote the consumption of chrysanthemum as a functional tea.

Keywords: Anti-inflammatory; Antioxidant; Chemical composition; Chrysanthemum tea.

MeSH terms

Animals
Anti-Inflammatory Agents / chemistry*
Anti-Inflammatory Agents / pharmacology
Antioxidants / chemistry*
Cell Line
Chromatography, High Pressure Liquid
Chrysanthemum / chemistry*
Chrysanthemum / metabolism
Cytokines / genetics
Cytokines / metabolism
Humans
Hydrogen Peroxide / pharmacology
Lipopolysaccharides / pharmacology
Macrophages / cytology
Macrophages / drug effects
Macrophages / metabolism
Mice
Oxidative Stress / drug effects
Phenols / analysis
Phenols / chemistry
Plant Extracts / chemistry
RAW 264.7 Cells
Spectrometry, Mass, Electrospray Ionization

Substances

Anti-Inflammatory Agents
Antioxidants
Cytokines
Lipopolysaccharides
Phenols
Plant Extracts
Hydrogen Peroxide