Mycoplasma pneumoniae is a threat to public health. This pathogen caused an epidemic in Hong Kong during the years 2015-2018. The reproduction number during the initial epidemic was estimated to be 1.7 for macrolide-resistant M. pneumoniae (MRMP) and 1.4 for macrolide-sensitive M. pneumoniae (MSMP). During 2016-2018, the reproduction number remained stable at around 1.0 for both MRMP and MSMP. Phase-shifting and changes in the leading-status between the transmissibilities of MSMP and MRMP were found.
Keywords: Antibiotic resistance; Mycoplasma pneumoniae; Reproduction number; Statistical analysis; Wavelet analysis.
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