Structural characterization and biological evaluation of chemical constituents from Ilex cornuta

J Asian Nat Prod Res. 2020 Apr;22(4):316-328. doi: 10.1080/10286020.2019.1570160. Epub 2019 Mar 1.

Abstract

One new ursane-type triterpenoid (1), one new ursane-type triterpenoid glycoside (2), and one new oleanane-type triterpenoid glycoside (3), along with 20 known compounds, were isolated from the leaves of Ilex cornuta. The structures of these natural products were elucidated on the basis of detailed spectroscopic analyses and chemical derivation. Our biological evaluation established that selective compounds showed moderate to significant antioxidant activities in the 1,1-diphenyl-2-picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) methods.

Keywords: Aquifoliaceae; Ilex cornuta; antioxidant activity; phenolic compound; triterpenoid; triterpenoid saponin.

MeSH terms

  • Glycosides
  • Ilex*
  • Molecular Structure
  • Plant Leaves
  • Plant Roots
  • Triterpenes*

Substances

  • Glycosides
  • Triterpenes