Multimodel MRI features of an intracranial juvenile Xanthogranuloma

Childs Nerv Syst. 2019 May;35(5):871-874. doi: 10.1007/s00381-019-04102-6. Epub 2019 Feb 28.

Abstract

Juvenile xanthogranuloma (JXG) is a benign, self-limiting histiocytic disorder of infancy and early childhood, usually presented as a single or multiple cutaneous lesions. The central nervous system is rarely affected by JXG. There were only a few reports of intracranial JXG cases which described its features on MR spectroscopy (MRS) and diffusion-weighted imaging (DWI), but its features on susceptibility-weighted imaging (SWI) and perfusion-weighted imaging (PWI) have not been reported yet. Here, we reported an intracranial JXG case which underwent multimodal MRI examinations including DWI, SWI, and PWI. The multimodal MRI provided a thorough insight into this disease and we found that intense enhancement and high perfusion may be important clues for the diagnosis.

Keywords: Diffusion-weighted imaging; Magnetic resonance imaging; Perfusion-weighted imaging; Susceptibility-weighted imaging; Xanthogranuloma, juvenile.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Diffusion Magnetic Resonance Imaging / methods
  • Female
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Spectroscopy / methods*
  • Multimodal Imaging / methods
  • Xanthogranuloma, Juvenile / diagnostic imaging*
  • Xanthogranuloma, Juvenile / surgery*