Abstract
We analyzed 14 patients in our hospital, who underwent levodopa-carbidopa intestinal gel (LCIG) treatment through a percutaneous endoscopic gastrojejunostomy (PEG-J). The PEG-J related complications were observed in 10 patients (71.4%). Detailed complications are as followings: J-tube related complications such as kinking (3 cases, 21.4%), pump malfunctions (3 cases, 21.4%), skin troubles in the gastrostoma (7 cases, 50.0%), duodenal perforation, peritonitis, and ulcers (2 cases, 14.3%). These results indicated that the sufficient care for PEG-J associated complications are important in LCIG treatment.
Keywords:
Parkinson’s disease; complications; levodopa-carbidopa intestinal gel treatment; percutaneous endoscopic gastrojejunostomy.
MeSH terms
-
Adult
-
Aged
-
Antiparkinson Agents / administration & dosage*
-
Carbidopa / administration & dosage*
-
Drug Combinations
-
Duodenal Diseases / epidemiology
-
Duodenal Diseases / etiology
-
Duodenal Ulcer / epidemiology
-
Duodenal Ulcer / etiology
-
Endoscopy, Gastrointestinal / adverse effects*
-
Endoscopy, Gastrointestinal / instrumentation
-
Endoscopy, Gastrointestinal / methods
-
Female
-
Gastrostomy / adverse effects*
-
Gastrostomy / instrumentation
-
Gastrostomy / methods
-
Gels
-
Humans
-
Intestinal Perforation / epidemiology
-
Intestinal Perforation / etiology
-
Jejunostomy / adverse effects*
-
Jejunostomy / instrumentation
-
Jejunostomy / methods
-
Levodopa / administration & dosage*
-
Male
-
Middle Aged
-
Parkinson Disease / drug therapy*
-
Peritonitis / epidemiology
-
Peritonitis / etiology
-
Retrospective Studies
-
Skin Diseases / epidemiology
-
Skin Diseases / etiology
-
Surgical Stomas
Substances
-
Antiparkinson Agents
-
Drug Combinations
-
Gels
-
carbidopa, levodopa drug combination
-
Levodopa
-
Carbidopa