Effect of patent ductus arteriosus on the heart in preterm infants

Ranjit Philip; Jeffrey A Towbin; Shyam Sathanandam; Jason Goldberg; Thomas Yohannan; Nithya Swaminathan; Jason Nathaniel Johnson

doi:10.1111/chd.12701

Effect of patent ductus arteriosus on the heart in preterm infants

Congenit Heart Dis. 2019 Jan;14(1):33-36. doi: 10.1111/chd.12701.

Authors

Ranjit Philip¹, Jeffrey A Towbin¹, Shyam Sathanandam¹, Jason Goldberg¹, Thomas Yohannan¹, Nithya Swaminathan¹, Jason Nathaniel Johnson^{1

2}

Affiliations

¹ Division of Pediatric Cardiology, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis, Tennessee.
² Division of Pediatric Radiology, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis, Tennessee.

PMID: 30811789
DOI: 10.1111/chd.12701

Abstract

There continues to be controversy on the long-term effects of a patent ductus arteriosus (PDA) and its management. However, the hemodynamic effects of a large PDA in a preterm infant are well known. This article aims to provide insight into the adaptive changes and remodeling effects of a PDA on the myocardium in preterm infants.

Keywords: congestive heart failure; neonatology; patent ductus arteriosus; pediatrics; preterm infant; surgical ligation; transcatheter device closure.

Publication types

Review

MeSH terms

Disease Progression
Ductus Arteriosus, Patent / physiopathology*
Gestational Age
Humans
Infant, Newborn
Infant, Premature*
Ventricular Function, Left / physiology*
Ventricular Remodeling / physiology*