Abstract
In this work, we propose a pH-regulated and target-activated fluorescent nanoprobe for highly selective monitoring of lysosomal azoreductase under hypoxia in living cells. We expect it will offer a potentially rich opportunity to understand the physiological processes of lysosomes under hypoxic conditions.
MeSH terms
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Adsorption
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Carbon Dioxide / isolation & purification*
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Cell Hypoxia*
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Fluorescent Dyes / chemistry*
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Humans
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Hydrogen-Ion Concentration
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Kinetics
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Lysosomes / enzymology*
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MCF-7 Cells
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NADH, NADPH Oxidoreductases / metabolism*
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Nanostructures*
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Natural Gas*
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Nitroreductases
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Phase Transition
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Thermodynamics
Substances
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Fluorescent Dyes
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Natural Gas
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Carbon Dioxide
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NADH, NADPH Oxidoreductases
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Nitroreductases
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azoreductase