Consumption of antibiotics by children in Greece: a cross-sectional study

Int J Pediatr Adolesc Med. 2017 Sep;4(3):108-111. doi: 10.1016/j.ijpam.2017.04.002. Epub 2017 Jun 23.

Abstract

Background: Greece is among the European countries with the highest consumption of antibiotics.

Objectives: To study the rates and characteristics of consumption of antibiotics in the community by children in Greece.

Methods: Questionnaire-based study of parents of hospitalized children.

Results: A total of 549 children were studied; 247 (45%) received at least one course of antibiotics the previous year (mean number of antibiotic courses the past year: 1.9), including 427 (91.8%) following examination by a pediatrician, 6 (1.3%) following phone consultation, 2 (0.4%) following suggestion by a pharmacist and 2 (0.4%) as self-medication. Prevalent reasons for antibiotic consumption were acute otitis media (AOM) (27.3%), pharyngotonsillitiss (25.4%), and bronchitis (17.8%). Amoxicillin-clavulanate was the prevalent antibiotic for pharyngotonsillitis, urinary tract infection (UTI) and skin infection (30.5%, 35.7% and 36.4% of cases, respectively), amoxicillin for AOM and pneumonia (32.3% and 36.4% of cases, respectively), and clarithromycin for bronchitis (27.7%). We found 84.3%, 81.9%, 64.3%, 63.7%, and 50% of parents reporting treatment consisted with the national guidelines for AOM, pneumonia, UTI, skin infection, and pharyngotonsillitis, respectively. In the multivariate analysis, an age of 1-5 years and asthma were significantly associated with a higher probability for antibiotic consumption.

Conclusions: Antibiotic consumption of children in Greece is mainly driven by pediatricians. Continuing medical education is expected to further improve antibiotic prescription practices by pediatricians.

Keywords: Antibiotics; Children; Community; Consumption; Pediatrics.