Abstract
Room temperature phosphorescent (RTP) γ-CD-CB[6]-cowheeled [4]rotaxanes were synthesized by implanting a naphthalene axle into the cavity of iodine-substituted γ-CDs. The strong green RTP was quenched exclusively by Trp while no RTP quenching was observed with other major physiological amino acids or with the Trp-containing protein HSA, demonstrating a highly specific sensing of free Trp.
MeSH terms
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Bridged-Ring Compounds / chemical synthesis
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Bridged-Ring Compounds / chemistry*
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Humans
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Imidazoles / chemical synthesis
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Imidazoles / chemistry*
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Luminescent Agents / chemical synthesis
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Luminescent Agents / chemistry*
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Luminescent Measurements / methods
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Rotaxanes / chemical synthesis
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Rotaxanes / chemistry*
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Temperature
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Tryptophan / analysis*
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Tryptophan / blood
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gamma-Cyclodextrins / chemical synthesis
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gamma-Cyclodextrins / chemistry*
Substances
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Bridged-Ring Compounds
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Imidazoles
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Luminescent Agents
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Rotaxanes
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gamma-Cyclodextrins
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cucurbit(6)uril
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Tryptophan
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gamma-cyclodextrin