Dermatophyte Immune Memory Is Only Skin-Deep

Akash H Verma; Sarah L Gaffen

doi:10.1016/j.jid.2018.10.022

Dermatophyte Immune Memory Is Only Skin-Deep

J Invest Dermatol. 2019 Mar;139(3):517-519. doi: 10.1016/j.jid.2018.10.022.

Authors

Akash H Verma¹, Sarah L Gaffen²

Affiliations

¹ Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
² Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. Electronic address: Sarah.Gaffen@Pitt.edu.

Abstract

A new report in this issue of Journal of Investigative Dermatology reveals a role for IL-17 and IFN-gamma, signature cytokines of T-helper 17 and T-helper 1 cells, in immunity to Trichophyton benhamiae (Heinen et al., 2018). While there have been many recent advances in understanding host defenses against common fungi, this work illuminates not only adaptive immunity, but also innate immune responses to dermatophytosis.

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

Adaptive Immunity
Arthrodermataceae*
Dermatomycoses*
Humans
Immunity, Innate
Immunologic Memory
Tinea*

Abstract

Publication types

MeSH terms

Grants and funding