Cultural Adaptation and Validation of the Inflammatory Bowel Disease Disability Index in a Spanish Population and Its Association with Sociodemographic and Clinical Factors

Int J Environ Res Public Health. 2019 Feb 21;16(4):635. doi: 10.3390/ijerph16040635.

Abstract

Inflammatory bowel diseases generate disability. We aimed to adapt and validate the Inflammatory Bowel Disease Disability Index in a Spanish population and to analyze the sociodemographic and clinical factors associated with disability in patients with Crohn's disease and ulcerative colitis. Cultural adaptation and validation of psychometric properties in the index were done, along with an observational, cross-sectional, and analytical approach to determine associations with sociodemographic and clinical factors. Sociodemographic data, quality of life (using the Inflammatory Bowel Disease Questionnaire-32), and indicators of disease activity were collected, among others. A total of 170 subjects participated. The index showed high internal consistency, with a Cronbach's alpha of 0.869 and concurrent validity with the Inflammatory Bowel Disease Questionnaire-32 (r = 0.723, p < 0.001). The average score of the index was -3.91. Greater degrees of disability were found in women (mean = -6.77) than in men (mean = -1.25) (p = 0.018), in patients with Crohn's disease (mean = -5.94) rather than those with ulcerative colitis (mean = -0.94) (p = 0.028), and in patients in the moderately active disease phase (mean = -20.94) rather than those in the mildly active disease phase (mean = -2.65) and/or those in remission (mean = -1.40) (p < 0.001). The Disability Index is a valid tool for the Spanish population and is associated with sex, type of illness, and disease activity. It is a useful index in evaluating and monitoring disability in patients with inflammatory bowel disease.

Keywords: disability; inflammatory bowel disease; quality of life.

Publication types

  • Observational Study
  • Validation Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Colitis, Ulcerative / epidemiology
  • Colitis, Ulcerative / pathology
  • Crohn Disease / epidemiology
  • Crohn Disease / pathology
  • Cross-Cultural Comparison
  • Cross-Sectional Studies
  • Culture
  • Disabled Persons
  • Female
  • Humans
  • Inflammatory Bowel Diseases / epidemiology*
  • Inflammatory Bowel Diseases / pathology*
  • Male
  • Middle Aged
  • Pilot Projects
  • Psychometrics
  • Quality of Life
  • Severity of Illness Index
  • Spain / epidemiology
  • Surveys and Questionnaires
  • Young Adult