The Secret Life of IgE-Producing Cells

Carlos J Aranda; Maria A Curotto de Lafaille

doi:10.1016/j.immuni.2019.01.018

The Secret Life of IgE-Producing Cells

Immunity. 2019 Feb 19;50(2):285-287. doi: 10.1016/j.immuni.2019.01.018.

Authors

Carlos J Aranda¹, Maria A Curotto de Lafaille²

Affiliations

¹ Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
² Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA; Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA. Electronic address: maria.lafaille@med.nyu.edu.

Abstract

IgE antibodies are essential mediators of allergies. In a recent study in Science, Croote et al. (2018) characterize IgE cells isolated from individuals allergic to peanuts. Their findings provide insight into the differentiation of IgE cells in humans and have implications for our understanding of allergic disease.

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MeSH terms

Allergens*
B-Lymphocytes
Humans
Hypersensitivity*
Immunoglobulin E
Transcriptome

Substances

Allergens
Immunoglobulin E

Abstract

Publication types

MeSH terms

Substances

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