PROTEOSTASIS: A European Network to Break Barriers and Integrate Science on Protein Homeostasis

Nico Dissmeyer; Olivier Coux; Manuel S Rodriguez; Rosa Barrio; Core Group Members of PROTEOSTASIS

doi:10.1016/j.tibs.2019.01.007

PROTEOSTASIS: A European Network to Break Barriers and Integrate Science on Protein Homeostasis

Trends Biochem Sci. 2019 May;44(5):383-387. doi: 10.1016/j.tibs.2019.01.007. Epub 2019 Feb 16.

Authors

Nico Dissmeyer¹, Olivier Coux², Manuel S Rodriguez³, Rosa Barrio⁴; Core Group Members of PROTEOSTASIS⁵

Affiliations

¹ Leibniz Institute for Plant Biochemistry (IPB), D-06120 Halle, Germany.
² CRBM (Montpellier Cell Biology Research Center), University of Montpellier, CNRS, UMR5237, F-34090 Montpellier, France. Electronic address: olivier.coux@crbm.cnrs.fr.
³ ITAV USR3505-IPBS CNRS-UPS, F-31106 Toulouse, France.
⁴ CIC bioGUNE, Asociación Centro de Investigación Cooperativa en Biociencias, 48160, Derio, Spain. Electronic address: rbarrio@cicbiogune.es.
⁵ For a full list of authors, please see Table S1 in the supplemental information online.

PMID: 30777377
DOI: 10.1016/j.tibs.2019.01.007

Abstract

Protein homeostasis (proteostasis) is at the core of cellular functions. The European network PROTEOSTASIS was created to steer research and foster collaborations in the interconnected fields of posttranslational modifications by ubiquitin family members and protein turnover by proteasome, autophagy, and lysosomal systems in health and diseases, across the kingdoms of life.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Autophagy
Europe
Homeostasis
Humans
Lysosomes / metabolism*
Proteasome Endopeptidase Complex / metabolism*
Protein Processing, Post-Translational
Proteostasis*
Ubiquitin / metabolism*

Substances

Ubiquitin
Proteasome Endopeptidase Complex