Controller for microfluidic large-scale integration

HardwareX. 2018 Apr:3:135-145. doi: 10.1016/j.ohx.2017.10.002. Epub 2017 Oct 31.

Abstract

Microfluidic devices with integrated valves provide precise, programmable fluid handling platforms for high-throughput biological or chemical assays. However, setting up the infrastructure to control such platforms often requires specific engineering expertise or expensive commercial solutions. To address these obstacles, we present a Kit for Arduino-based Transistor Array Actuation (KATARA), an open-source and low-cost Arduino-based controller that can drive 70 solenoid valves to pneumatically actuate integrated microfluidic valves. We include a python package with a GUI to control the KATARA from a personal computer. No programming experience is required.

Keywords: Arduino shield; Microfluidics; Multi-layer soft lithography; Open source hardware; Python; Solenoid valve.