Intraluminal three-dimensional optical coherence tomography - a tool for imaging of the Eustachian tube?

J Laryngol Otol. 2019 Feb;133(2):87-94. doi: 10.1017/S002221511800230X. Epub 2019 Feb 18.

Abstract

Objectives: The cause of Eustachian tube dysfunction often remains unclear. Therefore, this study aimed to examine the feasibility and possible diagnostic use of optical coherence tomography in the Eustachian tube ex vivo.

Methods: Two female blackface sheep cadaver heads were examined bilaterally. Three conditions of the Eustachian tube were investigated: closed (resting position), actively opened and stented. The findings were compared (and correlated) with segmented histological cross-sections.

Results: Intraluminal placement of the Eustachian tube with the optical coherence tomography catheter was performed without difficulty. Regarding the limited infiltration depth of optical coherence tomography, tissues can be differentiated. The localisation of the stent was accurate as was the lumen.

Conclusion: The application of optical coherence tomography in the Eustachian tube under these experimental conditions is considered to be a feasible, rapid and non-invasive diagnostic method, with possible diagnostic value for determining the luminal shape and superficial lining tissue of the Eustachian tube.

Keywords: Optical Coherence; Three Dimensional; Eustachian Tube; Imaging; Middle Ear Ventilation; Tomography.

MeSH terms

  • Animals
  • Cadaver
  • Disease Models, Animal
  • Ear Diseases / diagnosis*
  • Endoscopy / methods*
  • Eustachian Tube / diagnostic imaging*
  • Feasibility Studies
  • Female
  • Imaging, Three-Dimensional*
  • Sheep
  • Tomography, Optical Coherence / methods*